Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Topoisomerase IIα Inhibitor, TSC24
The Topoisomerase IIα Inhibitor, TSC24 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ α1-Antichymotrypsin, Human Plasma
Acute-phase protein present at ∽45mg/100mL in plasma.
MilliporeSigma™ Calbiochem™ AMPK Activator VI, RSVA314
The AMPK Activator VI, RSVA314 modulates the biological activity of AMPK. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ MMP-14 Substrate I, Fluorogenic
A specific fluorescence resonance energy transfer (FRET) peptide substrate for the detection of MMP activity.
MilliporeSigma™ Calbiochem™ Cdk9 Inhibitor II
The Cdk9 Inhibitor II, also referenced under CAS 140651-18-9, controls the biological activity of Cdk9. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Autophagy Inducer, STF-62247
A cell-permeable autophagy inducer that selectively induces non-apoptotic cell death in VHL-deficient, but not VHL-expressing, renal carcinoma cells both in vitro and in mice in vivo.
MilliporeSigma™ Calbiochem™ Mitochondrial Citrate Transport Protein (CTP) Inhibitor
The Mitochondrial Citrate Transport Protein (CTP) Inhibitor, also referenced under CAS 412940-35-3, controls the biological activity of Mitochondrial Citrate Transport Protein (CTP).
MilliporeSigma™ Calbiochem™ bpV(bipy)
A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation).
MilliporeSigma™ Calbiochem™ IDH2 Inhibitor, R140Q Somatic Mutant-Specific, AGI-6780
A cell-permeable inhibitor of isocitrate dehydrogenase 2 R140Q mutant-containing dimers. Has minimal effect on wild type dimer-catalyzed alpha-KG production.
MilliporeSigma™ Calbiochem™ PD 158780
A potent, cell-permeable, reversible, ATP-competitive inhibitor of the EGFR tyrosine kinase activity (IC50 = 8 pM).
MilliporeSigma™ Calbiochem™ SHIP2 Inhibitor, AS1938909
The SHIP2 Inhibitor, AS1938909 controls the biological activity of SHIP2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ β-Secretase Inhibitor IV
β-Secretase Inhibitor IV, CAS 797035-11-1, is a cell-permeable inhibitor that binds to BACE-1 active site and blocks its proteolytic activity (IC50 = 15 nM for human BACE-1).
MilliporeSigma™ Calbiochem™ (R)-(+)-SKF38393 Hydrochloride
A benzazepine derivative that acts as a selective Dopamine D1 /D5 receptor partial a
MilliporeSigma™ Calbiochem™ β-Glucuronidase Inhibitor
The β-Glucuronidase Inhibitor controls the biological activity of β-Glucuronidase.
MilliporeSigma™ Calbiochem™ MIF Antagonist III, 4-IPP
A cell-permeable iodo-pyrimidine compound that covalently modifies MIF N-terminal proline and exhibits higher MIF inhibitory potency than ISO-1 (Cat